Effect of Transcriptional Regulatory Factor FoxO3a on Central Nervous System Oxygen Toxicity
نویسندگان
چکیده
منابع مشابه
Central nervous system oxygen toxicity during routine hyperbaric oxygen therapy.
Hyperbaric oxygen therapy is associated with a recognized risk for clinically apparent central nervous system (CNS) toxicity. The risk for oxygen-induced convulsions during routine hyperbaric treatment of most routine conditions is extremely low. However, reports from the 1980's describing the incidence of CNS oxygen toxicity differ significantly from more recent reports since 1996. This retros...
متن کاملCentral Nervous System Oxygen Toxicity and Hyperbaric Oxygen Seizures.
INTRODUCTION The use of hyperbaric oxygen (O2) as a therapeutic agent carries with it the risk of central nervous system (CNS) O2 toxicity. METHODS To further the understanding of this risk and the nature of its molecular mechanism, a review was conducted on the literature from various fields. RESULTS Numerous physiological changes are produced by increased partial pressures of oxygen (Po2)...
متن کاملHumidity does not affect central nervous system oxygen toxicity.
Central nervous system (CNS) oxygen toxicity can occur as convulsions and loss of consciousness when hyperbaric oxygen is breathed in diving and hyperbaric medical therapy. Lin and Jamieson (J Appl Physiol 75: 1980-1983, 1993) reported that humidity in the inspired gas enhances CNS oxygen toxicity. Because alveolar gas is fully saturated with water vapor, we could not see a cause and effect and...
متن کاملBidirectional influences of acetazolamide on central nervous system oxygen toxicity of rats.
Central nervous system oxygen toxicity, which occurs during diving and hyperbaric oxygen treatment, can lead to very dangerous situations, and it is of great importance to explore its mechanisms. We have speculated that cerebral blood flow plays a pivotal role in its occurrence. Except for acting as an anticonvulsant in clinical applications, acetazolamide is also a vasodilator used in both cli...
متن کاملCentral nervous system toxicity of metallic nanoparticles
Nanomaterials (NMs) are increasingly used for the therapy, diagnosis, and monitoring of disease- or drug-induced mechanisms in the human biological system. In view of their small size, after certain modifications, NMs have the capacity to bypass or cross the blood-brain barrier. Nanotechnology is particularly advantageous in the field of neurology. Examples may include the utilization of nanopa...
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ژورنال
عنوان ژورنال: Frontiers in Physiology
سال: 2020
ISSN: 1664-042X
DOI: 10.3389/fphys.2020.596326